Search on: PROTEIN KINASE A ANCHOR PROTEINS 
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Descriptor English:   A Kinase Anchor Proteins 
Descriptor Spanish:   Proteínas de Anclaje a la Quinasa A 
Descriptor Portuguese:   Proteínas de Ancoragem à Quinase A 
Synonyms English:   A-Kinase Anchor Proteins
Anchor Proteins, A-Kinase
Protein Kinase A Anchor Proteins  
Tree Number:   D12.644.360.024.065
D12.776.157.057.003
D12.776.476.024.069
Definition English:   A structurally-diverse family of intracellular-signaling adaptor proteins that selectively tether specific protein kinase A subtypes to distinct subcellular sites. They play a role in focusing the PROTEIN KINASE A activity toward relevant substrates. Over fifty members of this family exist, most of which bind specifically to regulatory subunits of CYCLIC AMP-DEPENDENT PROTEIN KINASE TYPE II such as CAMP PROTEIN KINASE RIIALPHA or CAMP PROTEIN KINASE RIIBETA. 
History Note English:   2008 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UR urine  
Record Number:   52783 
Unique Identifier:   D054758 

Occurrence in VHL:
 

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